Introduction

Our Vision

To be a global leader in Mechanobiology research and create new knowledge and technologies for the enhancement of human health

Ten years ago, the Mechanobiology Institute (MBI) was created jointly by the Singapore National Research Foundation, the Ministry of Education and the National University of Singapore as the 4th Research Centre of Excellence, as part of Singapore’s bold effort to build world-class investigator-led research centres with a global impact and aligned with the long-term strategic interests of the country. With the continued resources to recruit top scientific talents and build facilities in nanotechnology, modern microscopy, molecular biology and genomics, MBI today is working hard to solve key problems of cellular mechanics that underlie normal development, physiology and aging, as well as a variety of maladies from cancer to age-related diseases.

Mechanobiology is an emerging discipline, one that demands dedicated researchers with innovative and collaborative spirit, the courage to think out of the box, and the drive to succeed.

Understanding biological forces requires a multi-scale systems perspective. MBInfo is an online platform created to provide a modular understanding of dynamic processes across molecular, cellular and tissue levels. Through comparative analysis of how dynamic processes are altered in normal and diseased cells and tissues, the knowledge gained may lead to a “tissue repair manual” for the better maintenance of healthy functions and treatment of degenerative diseases. The deliverables of this integrated knowledge of cellular and molecular mechanics will be accomplished through interdisciplinary collaborations across Singapore and international research communities in medicine, biology, chemistry, physics, engineering and computing. MBI endeavors to serve as a leader and nucleus in this effort.

Mechanobiology is an emerging discipline, one that demands dedicated researchers with innovative and collaborative spirit, the courage to think out of the box, and the drive to succeed. Here at MBI we are creating a new and powerful community of scientists and engineers committed to the advancement of mechanobiology and its application to improving human health.

SIMBA equpiment is available for booking at competitive rates.

The Biophotonic Breakfast meets the first Thursday of the month at 10am at the T-Lab, level 5, and with a simultaneously streamed session via ZOOM. Initiated by SiMBA, the Biophotonic Breakfas provides a breakfast ‘journal and method club’ dedicated to the biophotonic field. Talks focus on cutting-edge methods and new techniques in the field of microscopy, image analysis, correlative microscopy with EM, and imaging techniques in a broad sense (ie :spatial transcriptomics), with a touch of biology. The main idea is “to share and initiate brand new tech ” with some croissants (yes we can !), and so no pressure. The talks are open to everyone at MBI and members of LSI/Singascope and are an excellent opportunity for students and postdocs to demonstrate their interest in specific techniques and new ideas in a collaborative environment. Eligible candidates who wish to present are encouraged to contact SiMBA at simba-mbi.com.